Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Gt(ROSA)26Sortm1(CAG-RABVgp4,-TVA)Arenk
Name:	gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Benjamin Arenkiel
MGI ID:	MGI:5550559
Synonyms:	RPhiGT
Gene:	Gt(ROSA)26Sor  Location: Chr6:113044389-113054205 bp, - strand  Genetic Position: Chr6, 52.73 cM
Alliance:	Gt(ROSA)26Sortm1(CAG-RABVgp4,-TVA)Arenk page

Germline Transmission:	Earliest citation of germline transmission: J:206510
Parent Cell Line:	E14 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Conditional ready, Inserted expressed sequence, Reporter) Mutation:    Insertion   Mutation details: The targeting vector contains a loxP-flanked STOP cassette, recombinant rabies glycoprotein G, IRES sequence and TVA (avian leukosis and sarcoma virus subgroup A receptor, chicken) under the control of CAG (CMV enhancer/chicken beta-actin promoter). Expression of the rabies glycoprotein is blocked by the loxP-flanked STOP fragment. (J:206510)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:	942 strains or lines available

Original:	J:206510 Takatoh J, et al., New modules are added to vibrissal premotor circuitry with the emergence of exploratory whisking. Neuron. 2013 Jan 23;77(2):346-60
All:	17 reference(s)