Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Cishtm1.1Khk
Name:	cytokine inducible SH2-containing protein; targeted mutation 1.1, Klaus H Kaestner
MGI ID:	MGI:5550527
Synonyms:	CishloxP
Gene:	Cish  Location: Chr9:107173858-107179983 bp, + strand  Genetic Position: Chr9, 57.99 cM
Alliance:	Cishtm1.1Khk page

Germline Transmission:	Earliest citation of germline transmission: J:203844
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	C57BL/6

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: An FRT-flanked self-excising neomycin resistance cassette with a 3' loxP site was inserted upstream of exon 2. An additional loxP site was inserted downstream of exon 2. The final allele lacks the neomycin resistance cassette. (J:203844)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cish Mutation:	22 strains or lines available

Original:	J:203844 Jiao Y, et al., CISH has no non-redundant functions in glucose homeostasis or beta cell proliferation during pregnancy in mice. Diabetologia. 2013 Nov;56(11):2435-45
All:	1 reference(s)