Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Casq2tm1b(KOMP)Wtsi
Name:	calsequestrin 2; targeted mutation 1b, Wellcome Trust Sanger Institute
MGI ID:	MGI:5548421
Gene:	Casq2  Location: Chr3:101993731-102053830 bp, + strand  Genetic Position: Chr3, 44.3 cM, cytoband F3
Alliance:	Casq2tm1b(KOMP)Wtsi page
IMPC:	Casq2 gene page

Mutant Cell Line:	EPD0162_3_H09
Germline Transmission:	Earliest citation of germline transmission: J:204739
Parent Cell Line:	JM8.N4 (ES Cell)
Strain of Origin:	C57BL/6N
Project Collection:	KOMP-CSD

Allele Type:    Targeted (Null/knockout, Reporter) Mutations:    Insertion, Intragenic deletion     Vector: L1L2_Bact_P   Mutation details: Cre-mediated excision of the parental Casq2tm1a(KOMP)Wtsi allele resulted in the removal of the promoter-driven neomycin selection cassette and critical exon(s) leaving behind the inserted lacZ reporter sequence. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml. (J:204739)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	20 assay results
In Structures Affected by this Mutation:	3 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Casq2 Mutation:	34 strains or lines available

Original:	J:204739 International Knockout Mouse Consortium, MGI download of modified allele data from IKMC and creation of new knockout alleles. Database Download. 2014-2023;
All:	3 reference(s)