Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Entpd2tm1Srob
Name:	ectonucleoside triphosphate diphosphohydrolase 2; targeted mutation 1, Simon C Robson
MGI ID:	MGI:5545886
Gene:	Entpd2  Location: Chr2:25285886-25291333 bp, + strand  Genetic Position: Chr2, 17.22 cM
Alliance:	Entpd2tm1Srob page

Germline Transmission:	Earliest citation of germline transmission: J:200972
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A floxed neo cassette replaced exons 1 and 2 including the promoter region via homologous recombination. RT-PCR analysis confirmed the absence of mRNA in taste buds from homozygous mice. (J:200972)

Generation of the Entpd2tm1Srob allele

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Entpd2 Mutation:	25 strains or lines available

Original:	J:200972 Vandenbeuch A, et al., Role of the ectonucleotidase NTPDase2 in taste bud function. Proc Natl Acad Sci U S A. 2013 Sep 3;110(36):14789-94
All:	3 reference(s)