Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Wwtr1tm1.2Eno
Name:	WW domain containing transcription regulator 1; targeted mutation 1.2, Eric N Olson
MGI ID:	MGI:5544290
Gene:	Wwtr1  Location: Chr3:57363070-57483331 bp, - strand  Genetic Position: Chr3, 27.74 cM
Alliance:	Wwtr1tm1.2Eno page

Germline Transmission:	Earliest citation of germline transmission: J:200670
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129S/SvEv

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A loxP site was inserted upstream of exon 3 and an FRT flanked neo cassette and loxP site were inserted downstream of exon 3. Recombinase mediated recombination removed the neo cassette and exon 3. (J:200670)

Generation of the Wwtr1tm1.1Eno and Wwtr1tm1.2Eno alleles

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

6 assay results

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Wwtr1 Mutation:	23 strains or lines available

Original:	J:200670 Xin M, et al., Hippo pathway effector Yap promotes cardiac regeneration. Proc Natl Acad Sci U S A. 2013 Aug 20;110(34):13839-44
All:	4 reference(s)