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Septin9tm2.2Emfu
Targeted Allele Detail
Summary
Symbol: Septin9tm2.2Emfu
Name: septin 9; targeted mutation 2.2, Ernst-Martin Fuchtbauer
MGI ID: MGI:5544191
Synonyms: Sept9del
Gene: Septin9  Location: Chr11:117090487-117253151 bp, + strand  Genetic Position: Chr11, 82.61 cM
Alliance: Septin9tm2.2Emfu page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:205180
Parent Cell Line:  CJ7 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA loxP site was inserted upstream of exon 2. An FRT-flanked neomycin resistance cassette with a 5' loxP site was inserted downstream of exon 5. Flp-mediated recombination removed the neomycin resistance cassette. Cre-mediated recombination removed exons 2 through 5. (J:205180)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Septin9 Mutation:  199 strains or lines available
References
Original:  J:205180 Fuchtbauer A, et al., Septin9 is involved in septin filament formation and cellular stability. Biol Chem. 2011 Aug;392(8-9):769-77
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory