Summary | Mutation origin | Mutation description | Expression | Find Mice (IMSR) | References

Symbol:	Hltftm1.1Geno
Name:	helicase-like transcription factor; targeted mutation 1.1, Genoway
MGI ID:	MGI:5532312
Gene:	Hltf  Location: Chr3:20111975-20172654 bp, + strand  Genetic Position: Chr3, 6.15 cM
Alliance:	Hltftm1.1Geno page

Germline Transmission:	Earliest citation of germline transmission: J:203735
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129S2/SvPas

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: A loxP site was inserted upstream of exon 11. An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted downstream of exon 12. Flp-mediated recombination removed the neomycin resistance cassette and left exons 11 and 12 floxed. (J:203735)

Generation of the Hltftm1.2Geno allele

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hltf Mutation:	47 strains or lines available

Original:	J:203735 Helmer RA, et al., Role of helicase-like transcription factor (hltf) in the G2/m transition and apoptosis in brain. PLoS One. 2013;8(6):e66799
All:	2 reference(s)