Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	Slc4a11tm1.1Jrcy
Name:	solute carrier family 4, sodium bicarbonate transporter-like, member 11; targeted mutation 1.1, Joseph R Casey
MGI ID:	MGI:5524270
Gene:	Slc4a11  Location: Chr2:130526033-130539439 bp, - strand  Genetic Position: Chr2, 63.24 cM
Alliance:	Slc4a11tm1.1Jrcy page

Germline Transmission:	Earliest citation of germline transmission: J:202267
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exons 9 through 13 were floxed. Cre-mediated recombination removed exons 9 through 13. Immunohistochemistry confirmed the absence of protein expression in the cornea. (J:202267)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

5 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Slc4a11 Mutation:	50 strains or lines available

Original:	J:202267 Vilas GL, et al., Transmembrane water-flux through SLC4A11: a route defective in genetic corneal diseases. Hum Mol Genet. 2013 Nov 15;22(22):4579-90
All:	7 reference(s)