Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Asah1tm1.1Jhkh
Name:	N-acylsphingosine amidohydrolase 1; targeted mutation 1.1, Johannes Kornhuber
MGI ID:	MGI:5523898
Gene:	Asah1  Location: Chr8:41793234-41827810 bp, - strand  Genetic Position: Chr8, 23.89 cM
Alliance:	Asah1tm1.1Jhkh page

Germline Transmission:	Earliest citation of germline transmission: J:199833
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exon 1 was floxed and an FRT-lanked neomycin resistance cassette was inserted into the locus. Cre-mediated recombination removed exon 1. (J:199833)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Asah1 Mutation:	37 strains or lines available

Original:	J:199833 Gulbins E, et al., Acid sphingomyelinase-ceramide system mediates effects of antidepressant drugs. Nat Med. 2013 Jul;19(7):934-8
All:	3 reference(s)