Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Igf2bp1tm1Vssp
Name:	insulin-like growth factor 2 mRNA binding protein 1; targeted mutation 1, Vladimir S Spiegelman
MGI ID:	MGI:5523789
Synonyms:	Imp1-loxP
Gene:	Igf2bp1  Location: Chr11:95847989-95896766 bp, - strand  Genetic Position: Chr11, 59.08 cM
Alliance:	Igf2bp1tm1Vssp page

Germline Transmission:	Earliest citation of germline transmission: J:202774
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: A loxP site was inserted upstream of exon 5. An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted downstream of exon 6. (J:202774)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Igf2bp1 Mutation:	102 strains or lines available

Original:	J:202774 Hamilton KE, et al., IMP1 promotes tumor growth, dissemination and a tumor-initiating cell phenotype in colorectal cancer cell xenografts. Carcinogenesis. 2013 Nov;34(11):2647-54
All:	6 reference(s)