Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Fcgr4tm1Rav
Name:	Fc receptor, IgG, low affinity IV; targeted mutation 1, Jeffrey V Ravetch
MGI ID:	MGI:5521465
Synonyms:	Fcgr4flox
Gene:	Fcgr4  Location: Chr1:170846495-170857330 bp, + strand  Genetic Position: Chr1, 78.53 cM
Alliance:	Fcgr4tm1Rav page

Germline Transmission:	Earliest citation of germline transmission: J:167375
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	C57BL/6

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion     A loxP site was inserted upstream of exon 1 and loxP sites were inserted downstream of exon 3. (J:167375)

Generation of the Fcgr4tm1Rav and Fcgr4tm1.1Rav alleles

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fcgr4 Mutation:	22 strains or lines available

Original:	J:167375 Nimmerjahn F, et al., FcgammaRIV deletion reveals its central role for IgG2a and IgG2b activity in vivo. Proc Natl Acad Sci U S A. 2010 Nov 9;107(45):19396-401
All:	5 reference(s)