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Gal3st1tm1.1Hjg
Targeted Allele Detail
Summary
Symbol: Gal3st1tm1.1Hjg
Name: galactose-3-O-sulfotransferase 1; targeted mutation 1.1, Herman-Josef Grone
MGI ID: MGI:5520956
Synonyms: Cstfl
Gene: Gal3st1  Location: Chr11:3933636-3949326 bp, + strand  Genetic Position: Chr11, 2.81 cM, cytoband A1
Alliance: Gal3st1tm1.1Hjg page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:197393
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA loxP site followed by an FRT flanked neomycin resistance cassette was inserted 5' of the second coding exon and a second loxP site was inserted downstream of this exon. Flp recombinase expression in properly targeted mice excised the selection cassette leaving the second coding exon flanked by loxP sites. (J:197393)
Generation of the Gal3st1tm1.1Hjg allele
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gal3st1 Mutation:  22 strains or lines available
References
Original:  J:197393 Stettner P, et al., Sulfatides are required for renal adaptation to chronic metabolic acidosis. Proc Natl Acad Sci U S A. 2013 Jun 11;110(24):9998-10003
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory