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Adipor2tm1.1Kry
Targeted Allele Detail
Summary
Symbol: Adipor2tm1.1Kry
Name: adiponectin receptor 2; targeted mutation 1.1, Gerard Karsenty
MGI ID: MGI:5519976
Synonyms: AdipoR2fl
Gene: Adipor2  Location: Chr6:119330111-119394489 bp, - strand  Genetic Position: Chr6, 56.78 cM
Alliance: Adipor2tm1.1Kry page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:199264
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsAn FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted upstream of exon 5. An additional loxP site was inserted downstream of exon 7. Flp-mediated recombination removed the neomycin resistance cassette and left exons 5 through 7 floxed. (J:199264)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Adipor2 Mutation:  75 strains or lines available
References
Original:  J:199264 Kajimura D, et al., Adiponectin regulates bone mass via opposite central and peripheral mechanisms through FoxO1. Cell Metab. 2013 Jun 4;17(6):901-15
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory