Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Dpydtm1b(KOMP)Wtsi
Name:	dihydropyrimidine dehydrogenase; targeted mutation 1b, Wellcome Trust Sanger Institute
MGI ID:	MGI:5513767
Gene:	Dpyd  Location: Chr3:118355778-119226573 bp, + strand  Genetic Position: Chr3, 51.96 cM
Alliance:	Dpydtm1b(KOMP)Wtsi page
IMPC:	Dpyd gene page

Mutant Cell Line:	EPD0120_1_B11
Germline Transmission:	Earliest citation of germline transmission: J:200814
Parent Cell Line:	JM8.N4 (ES Cell)
Strain of Origin:	C57BL/6N
Project Collection:	KOMP-CSD

Allele Type:    Targeted (Null/knockout, Reporter) Mutations:    Insertion, Intragenic deletion     Vector: L1L2_Bact_P   Mutation details: Cre excision of MGI:4365089 tm1a allele removes the promoter-driven neo and critical exon(s) leaving behind the lacZ reporter (J:200814)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Dpyd Mutation:	65 strains or lines available

Original:	J:200814 Toronto Centre for Phenogenomics, Strains and alleles submitted by Toronto Centre for Phenogenomics (NorCOMM2, funded by Genome Canada and Ontario Genomics Institute OGI-051). MGI Direct Data Submission. 2013;
All:	4 reference(s)