Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol: Atp2b2Deaf11 Name: ATPase, Ca++ transporting, plasma membrane 2; deaf 11 MGI ID: MGI:5505456 Synonyms: Deaf11Mrci Gene: Atp2b2  Location: Chr6:113720803-114019574 bp, - strand  Genetic Position: Chr6, 52.85 cM Alliance: Atp2b2Deaf11 page

Abnormal cochlear hair cells in Atp2b2Deaf11/Atp2b2Deaf11 and Atp2b2Deaf13/Atp2b2Deaf13 mice Show the 1 phenotype image(s) involving this allele.

Strain of Origin:

BALB/c

Allele Type:    Chemically induced (ENU) Mutation:    Single point mutation   Mutation details: ENU mutagenesis induced a T to G point mutation in exon 17 that results in the amino acid substitution of serine for isoleucine at position 1023 (I1023S) in the tenth transmembrane domain. (J:199859) Inheritance:    Semidominant

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Atp2b2 Mutation:	66 strains or lines available

Original:	J:199859 Carpinelli MR, et al., Two ENU-induced alleles of Atp2b2 cause deafness in mice. PLoS One. 2013;8(6):e67479
All:	1 reference(s)