Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Lamc1tm1.2Strl
Name:	laminin, gamma 1; targeted mutation 1.2, Sidney Strickland
MGI ID:	MGI:5504479
Gene:	Lamc1  Location: Chr1:153094668-153208532 bp, - strand  Genetic Position: Chr1, 65.3 cM
Alliance:	Lamc1tm1.2Strl page

Germline Transmission:	Earliest citation of germline transmission: J:199683
Parent Cell Line:	E14 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exon 2 was flanked by single loxP sites. An frt flanked neomycin resistance cassette was inserted upstream of the floxed region, in intron 1. Cre-mediated recombination removed exon 2. (J:199683)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Lamc1 Mutation:	143 strains or lines available

Original:	J:199683 McKee KK, et al., Schwann cell myelination requires integration of laminin activities. J Cell Sci. 2012 Oct 1;125(Pt 19):4609-19
All:	1 reference(s)