Summary | Transgene origin | Transgene description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tg(CAG-Bgeo,-Nkx6-1,-EGFP)#Msan
Name:	transgene insertion, Maike Sander
MGI ID:	MGI:5501130
Synonyms:	CAG-Bgeo,-Nkx6.1,-eGFP, Nkx6.1OE
Transgene:	Tg(CAG-Bgeo,-Nkx6-1,-EGFP)#Msan  Location: unknown
Alliance:	Tg(CAG-Bgeo,-Nkx6-1,-EGFP)#Msan page

Strain of Origin:

(BALB/c x C57BL/6)F1

Transgene Type:    Transgenic (Inserted expressed sequence) Mutation:    Insertion   Tg(CAG-Bgeo,-Nkx6-1,-EGFP)#Msan expresses 1 gene Transgene expresses: Organism Expressed Gene Note mouse Nkx6-1 (MGI:1206039)   Mutation details: The CAG promoter drives ubiquitous expression of the mouse cDNA and IRES-EGFP preceded by a floxed beta-geo cassette. Two founder lines were established. The pound symbol (#) is used when no line is specified and/or lines are pooled. Cre-mediated recombination is required to removed the beta-geo cassette and allow for over-expression of the cDNA. (J:163847)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:163847 Schaffer AE, et al., Nkx6 transcription factors and Ptf1a function as antagonistic lineage determinants in multipotent pancreatic progenitors. Dev Cell. 2010 Jun 15;18(6):1022-9
All:	4 reference(s)