Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Apoetm1Rraf
Name:	apolipoprotein E; targeted mutation 1, David L Raffai
MGI ID:	MGI:5499980
Synonyms:	ApoeTh
Gene:	Apoe  Location: Chr7:19430034-19433113 bp, - strand  Genetic Position: Chr7, 9.94 cM
Alliance:	Apoetm1Rraf page

Germline Transmission:	Earliest citation of germline transmission: J:196923
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Conditional ready, Hypomorph) Mutations:    Insertion, Single point mutation   Mutation details: A floxed neomycin resistance cassette was inserted downstream of the exon 3. This allele is hypomorphic due to the presence of the floxed neomycin resistance cassette. (J:196923)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Apoe Mutation:	145 strains or lines available

Original:	J:196923 Eberle D, et al., Apolipoprotein E4 domain interaction accelerates diet-induced atherosclerosis in hypomorphic Arg-61 apoe mice. Arterioscler Thromb Vasc Biol. 2012 May;32(5):1116-23
All:	1 reference(s)