Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Bcl11atm1Mbu
Name:	BCL11 transcription factor A; targeted mutation 1, Meinrad Busslinger
MGI ID:	MGI:5496827
Synonyms:	Bcl11afl
Gene:	Bcl11a  Location: Chr11:24028056-24124123 bp, + strand  Genetic Position: Chr11, 14.41 cM
Alliance:	Bcl11atm1Mbu page

Germline Transmission:	Earliest citation of germline transmission: J:196405
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout, Reporter) Mutation:    Insertion   Mutation details: A loxP site was inserted upstream of exon 4. The construct targeted to exon 4 downstream of the stop condon contains (5' to 3') 6 polyadenylation sequences, a loxP site, unspecified recombination site, EGFP with a signal sequence, 2 polyadenylation sequences, neomycin resistance cassette and unspecified recombination site. (J:196405)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Bcl11a Mutation:	42 strains or lines available

Original:	J:196405 Esteghamat F, et al., Erythropoiesis and globin switching in compound Klf1::Bcl11a mutant mice. Blood. 2013 Mar 28;121(13):2553-62
All:	1 reference(s)