Gt(ROSA)26Sortm2(EIF1AX-bglA*)Dwi
Targeted Allele Detail
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Symbol: |
Gt(ROSA)26Sortm2(EIF1AX-bglA*)Dwi |
Name: |
gene trap ROSA 26, Philippe Soriano; targeted mutation 2, Douglas J Winton |
MGI ID: |
MGI:5495167 |
Synonyms: |
R26(SYNbglA)R |
Gene: |
Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
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Alliance: |
Gt(ROSA)26Sortm2(EIF1AX-bglA*)Dwi page
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Germline Transmission: |
Earliest citation of germline transmission:
J:196052
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Parent Cell Line: |
E14 (ES Cell)
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Strain of Origin: |
129P2/OlaHsd
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Allele Type: |
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Targeted (Conditional ready, Reporter) |
Mutation: |
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Insertion
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Mutation details: The construct targeted to the locus contains a floxed neomycin resistance/STOP cassette, the human EIF1AX promoter, a Caldocellum saccharolyticum gene that encodes a beta-glucosidase (bglA) and a polyadenylation sequence. Cre-mediated recombination is required to achieve expression of the reporter except in the small intestine where background activity is detected.
(J:196052)
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Generation of the Gt(ROSA)26Sortm2(EIF1AX-bglA*)Dwi allele |
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Gt(ROSA)26Sor Mutation: |
942 strains or lines available
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Original: |
J:196052 McCutcheon SC, et al., Characterization of a heat resistant beta-glucosidase as a new reporter in cells and mice. BMC Biol. 2010;8:89 |
All: |
1 reference(s) |
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