Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Stx16tm1b(KOMP)Wtsi
Name:	syntaxin 16; targeted mutation 1b, Wellcome Trust Sanger Institute
MGI ID:	MGI:5494475
Gene:	Stx16  Location: Chr2:173918101-173941564 bp, + strand  Genetic Position: Chr2, 97.85 cM
Alliance:	Stx16tm1b(KOMP)Wtsi page
IMPC:	Stx16 gene page

Mutant Cell Line:	EPD0025_3_F02
Germline Transmission:	Earliest citation of germline transmission: J:188991
Parent Cell Line:	JM8.N4 (ES Cell)
Strain of Origin:	C57BL/6N
Project Collection:	KOMP-CSD

Allele Type:    Targeted (Null/knockout, Reporter) Mutations:    Insertion, Intragenic deletion     Vector: L1L2_gt0   Mutation details: The L1L2_gt0 cassette was inserted at position 173933752 of Chromosome 2 upstream of the critical exon(s) (Build GRCm39). The cassette is composed of an FRT flanked lacZ/neomycin sequence followed by a loxP site. An additional loxP site was inserted downstream of the targeted exon(s) at position 173934606. The critical exon(s) were thus flanked by loxP sites and subsequent Cre-mediated excision removed the critical sequence and neomycin selection cassette resulting in a reporter knockout allele. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml. (J:148605, J:173534, J:188991)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	46 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Stx16 Mutation:	21 strains or lines available

Original:	J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012;
All:	6 reference(s)