Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Gt(ROSA)26Sortm19.1Sia
Name:	gene trap ROSA 26, Philippe Soriano; targeted mutation 19.1, Shinichi Aizawa
MGI ID:	MGI:5491541
Synonyms:	R26-mVenus-hGem, Rosa26mVenus-hGem(1/110)
Gene:	Gt(ROSA)26Sor  Location: Chr6:113044389-113054205 bp, - strand  Genetic Position: Chr6, 52.73 cM
Alliance:	Gt(ROSA)26Sortm19.1Sia page

Germline Transmission:	Earliest citation of germline transmission: J:196795
Parent Cell Line:	TT2 (ES Cell)
Strain of Origin:	(C57BL/6NCrlj x CBA/JNCrlj)F1

Allele Type:    Targeted (Reporter) Mutation:    Insertion   Mutation details: The targeting construct introduced a floxed STOP cassette followed by a mVenus and the ubiquitylation domains of human GMNN (amino acids 1 to 110) fusion. Cre-mediated recombination remvoed the STOP cassette. This fluorescent ubiquitylation-based cell cycle indicator accumulates in the nuclei during the S/G2/M phases of the cell cycle. (J:196795)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:	942 strains or lines available

Original:	J:196795 Abe T, et al., Visualization of cell cycle in mouse embryos with Fucci2 reporter directed by Rosa26 promoter. Development. 2013 Jan 1;140(1):237-46
All:	1 reference(s)