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Lcp2m1Khoe
Chemically induced Allele Detail
Nomenclature
Symbol: Lcp2m1Khoe
Name: lymphocyte cytosolic protein 2; mutation 1, Kasper Hoebe
MGI ID: MGI:5491498
Synonyms: ace, Slp-76ace
Gene: Lcp2  Location: Chr11:33996928-34042281 bp, + strand  Genetic Position: Chr11, 19.43 cM
Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Chemically induced (ENU)
Mutation:    Single point mutation
 
Mutation detailsENU mutagenesis induced a C to T point mutation that results in the amino acid substitution of isoleucine for threonine at position 428 (T428I). (J:229762)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Lcp2 Mutation:  32 strains or lines available
References
Original:  J:196519 Cashman S, et al., An ENU mutagenesis approach to dissect "self"-induced immune responses: Unraveling the genetic footprint of immunosurveillance. Oncoimmunology. 2012 Sep 1;1(6):856-862
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/18/2022
MGI 6.17
The Jackson Laboratory