Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Lcp2m1Khoe
Name:	lymphocyte cytosolic protein 2; mutation 1, Kasper Hoebe
MGI ID:	MGI:5491498
Synonyms:	ace, Slp-76ace
Gene:	Lcp2  Location: Chr11:33996928-34042281 bp, + strand  Genetic Position: Chr11, 19.43 cM
Alliance:	Lcp2m1Khoe page

Strain of Origin:

C57BL/6J

Allele Type:    Chemically induced (ENU) Mutation:    Single point mutation   Mutation details: ENU mutagenesis induced a C to T point mutation that results in the amino acid substitution of isoleucine for threonine at position 428 (T428I). (J:229762) Inheritance:    Recessive

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Lcp2 Mutation:	41 strains or lines available

Original:	J:196519 Cashman S, et al., An ENU mutagenesis approach to dissect "self"-induced immune responses: Unraveling the genetic footprint of immunosurveillance. Oncoimmunology. 2012 Sep 1;1(6):856-862
All:	4 reference(s)