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Gt(ROSA)26Sortm1(Kdm6b)Scla
Targeted Allele Detail
Summary
Symbol: Gt(ROSA)26Sortm1(Kdm6b)Scla
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Stefano Casola
MGI ID: MGI:5491321
Synonyms: Rosa26flSTOP-Jmjd3
Gene: Gt(ROSA)26Sor  Location: Chr6:113044389-113054205 bp, - strand  Genetic Position: Chr6, 52.73 cM
Alliance: Gt(ROSA)26Sortm1(Kdm6b)Scla page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:196346
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Targeted (Conditional ready, Inserted expressed sequence, Reporter)
Mutation:    Insertion
 
Gt(ROSA)26Sortm1(Kdm6b)Scla expresses 1 gene
 
Mutation detailsThe targeting construct inserted into the locus contained a splice acceptor, floxed neo/STOP cassette, cDNA, FRT-flanked IRES-EGFP and a polyadenylation sequence. (J:196346)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:  942 strains or lines available
References
Original:  J:196346 Burgold T, et al., The H3K27 demethylase JMJD3 is required for maintenance of the embryonic respiratory neuronal network, neonatal breathing, and survival. Cell Rep. 2012 Nov 29;2(5):1244-58
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory