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Etv2tm1Vkou
Targeted Allele Detail
Summary
Symbol: Etv2tm1Vkou
Name: ets variant 2; targeted mutation 1, Valerie Kouskoff
MGI ID: MGI:5474866
Synonyms: Etv2fl
Gene: Etv2  Location: Chr7:30333041-30335277 bp, - strand  Genetic Position: Chr7, 18.92 cM, cytoband A3
Alliance: Etv2tm1Vkou page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:194572
Parent Cell Line:  BK4 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA loxP site was inserted upstream of exon 1. An FRT-flanked neo cassette with a 3'loxP site was inserted downstream of exon 7. (J:194572)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Etv2 Mutation:  14 strains or lines available
Notes
ES cell line = Ainv18, a tet-on inducible ES cell line made in BK4 ES cells.
References
Original:  J:194572 Wareing S, et al., The Flk1-Cre-mediated deletion of ETV2 defines its narrow temporal requirement during embryonic hematopoietic development. Stem Cells. 2012 Jul;30(7):1521-31
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory