Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Gt(ROSA)26Sortm1(CAG-COP4/EGFP)Gmbk
Name:	gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Gero Miesenboeck
MGI ID:	MGI:5473413
Synonyms:	R26::ChR2-EGFP
Gene:	Gt(ROSA)26Sor  Location: Chr6:113044389-113054205 bp, - strand  Genetic Position: Chr6, 52.73 cM
Alliance:	Gt(ROSA)26Sortm1(CAG-COP4/EGFP)Gmbk page

Germline Transmission:	Earliest citation of germline transmission: J:194305
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Conditional ready, Reporter) Mutation:    Insertion   Mutation details: A transgene with the synthetic CAG promoter driving expression of a chlamyopsin 4 (COP4, or channelrhodopsin 2, ChR2) EGFP fusion protein (COP4/EGFP) following cre mediated removal a floxed transcripitonal stop signal (loxp sites flanking 3 copies of a polyadenylation signal was targeted to the Gt(ROSA)26Sor locus. (J:194305)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:	942 strains or lines available

Original:	J:194305 Katzel D, et al., The columnar and laminar organization of inhibitory connections to neocortical excitatory cells. Nat Neurosci. 2011 Jan;14(1):100-7
All:	2 reference(s)