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Cited2tm3.1Bha
Targeted Allele Detail
Summary
Symbol: Cited2tm3.1Bha
Name: Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2; q targeted mutation 3.1, Shoumo Bhattacharya
MGI ID: MGI:5472019
Synonyms: Cited2T166N
Gene: Cited2  Location: Chr10:17598966-17601422 bp, + strand  Genetic Position: Chr10, 7.18 cM, cytoband A2
Alliance: Cited2tm3.1Bha page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:192202
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Humanized sequence)
Mutations:    Insertion, Nucleotide substitutions
 
Mutation detailsA C to A transversion results in the amino acid substitution of arginine for threonine at position 166 (T166N). Flp-mediated recombination removed the FRT-flanked neo cassette inserted downstream of the modification. (J:192202)
Generation of the Cited2tm3.1Bha allele
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cited2 Mutation:  23 strains or lines available
References
Original:  J:192202 Chen CM, et al., Functional significance of SRJ domain mutations in CITED2. PLoS One. 2012;7(10):e46256
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory