Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Adcy7tm1.1Pcst
Name:	adenylate cyclase 7; targeted mutation 1.1, Paul C Sternweis
MGI ID:	MGI:5470143
Gene:	Adcy7  Location: Chr8:88999031-89056590 bp, + strand  Genetic Position: Chr8, 43.06 cM
Alliance:	Adcy7tm1.1Pcst page

Germline Transmission:	Earliest citation of germline transmission: J:191067
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: A loxP site was inserted upstream of exon 6. An FRT-flanked neo cassette with a 3'loxP site was inserted downstream of exon 6. Flp-mediated recombination removed the neo cassette and left exon 6 floxed. (J:191067)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Adcy7 Mutation:	59 strains or lines available

Original:	J:191067 Jiang LI, et al., Zymosan activates protein kinase A via adenylyl cyclase VII to modulate innate immune responses during inflammation. Mol Immunol. 2013 May;54(1):14-22
All:	2 reference(s)