Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Raratm3Ipc
Name:	retinoic acid receptor, alpha; targeted mutation 3, Pierre Chambon
MGI ID:	MGI:2386106
Synonyms:	RARalphafl, RARalpha L2
Gene:	Rara  Location: Chr11:98818644-98865768 bp, + strand  Genetic Position: Chr11, 62.76 cM, cytoband D-E1
Alliance:	Raratm3Ipc page

Germline Transmission:	Earliest citation of germline transmission: J:75135
Parent Cell Line:	D4 (ES Cell)
Strain of Origin:	129/Sv

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: Exon 8, which encodes most of the DNA binding domain, was left flanked by loxP sites after the in vitro cre-mediated excision of a selection cassette. Immunohistochemical analysis showed that protein expression was not affected by the presence of the loxP sites. (J:75135)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rara Mutation:	79 strains or lines available

Original:	J:75135 Chapellier B, et al., A conditional floxed (loxP-flanked) allele for the retinoic acid receptor alpha (RARalpha) gene. Genesis. 2002 Feb;32(2):87-90
All:	25 reference(s)