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Cnn1tm1.1Jomm
Targeted Allele Detail
Summary
Symbol: Cnn1tm1.1Jomm
Name: calponin 1; targeted mutation 1.1, Joseph M Miano
MGI ID: MGI:5463909
Gene: Cnn1  Location: Chr9:22010501-22020517 bp, + strand  Genetic Position: Chr9, 8.3 cM, cytoband A2-A4
Alliance: Cnn1tm1.1Jomm page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:191843
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA lacZ and floxed neo cassette replaced exon 1, intron 1 (containing 4 CArG elements), and exon 2. Cre-mediated recombination removed the neo cassette. No beta-galatosidase activity is detected in heterozygous mice. (J:191843)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cnn1 Mutation:  17 strains or lines available
References
Original:  J:191843 Long X, et al., Smooth muscle calponin: an unconventional CArG-dependent gene that antagonizes neointimal formation. Arterioscler Thromb Vasc Biol. 2011 Oct;31(10):2172-80
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory