Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Cacna1ctm1Ggm
Name:	calcium channel, voltage-dependent, L type, alpha 1C subunit; targeted mutation 1, Geoffrey G Murphy
MGI ID:	MGI:5446616
Synonyms:	Cav1.2f
Gene:	Cacna1c  Location: Chr6:118564201-119173851 bp, - strand  Genetic Position: Chr6, 55.86 cM
Alliance:	Cacna1ctm1Ggm page

Germline Transmission:	Earliest citation of germline transmission: J:189578
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: A loxP site was inserted into intron 1 and a floxed neo cassette was inserted into intron 2 via homologous recombination. (J:189578)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cacna1c Mutation:	141 strains or lines available

Original:	J:189578 White JA, et al., Conditional forebrain deletion of the L-type calcium channel Ca V 1.2 disrupts remote spatial memories in mice. Learn Mem. 2008 Jan;15(1):1-5
All:	8 reference(s)