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Il23rtm1.2Trin
Targeted Allele Detail
Summary
Symbol: Il23rtm1.2Trin
Name: interleukin 23 receptor; targeted mutation 1.2, Giorgio Trinchieri
MGI ID: MGI:5446610
Gene: Il23r  Location: Chr6:67399916-67468839 bp, - strand  Genetic Position: Chr6, 30.85 cM
Alliance: Il23rtm1.2Trin page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:189226
Parent Cell Line:  Bruce 4 (ES Cell)
Strain of Origin:  B6.Cg-Thy1a
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Cre-mediated recombination removed the neo cassettes, exon 2 and exon 3. (J:189226)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Il23r Mutation:  68 strains or lines available
References
Original:  J:189226 Grivennikov SI, et al., Adenoma-linked barrier defects and microbial products drive IL-23/IL-17-mediated tumour growth. Nature. 2012 Nov 8;491(7423):254-8
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory