Zfhx3tm1.2Jtd
Targeted Allele Detail
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Symbol: |
Zfhx3tm1.2Jtd |
Name: |
zinc finger homeobox 3; targeted mutation 1.2, Jin-Tang Dong |
MGI ID: |
MGI:5446506 |
Synonyms: |
Atbf1delta7and8 |
Gene: |
Zfhx3 Location: Chr8:109005975-109688268 bp, + strand Genetic Position: Chr8, 56.02 cM, cytoband E1
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Alliance: |
Zfhx3tm1.2Jtd page
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Reduced body size of Zfhx3tm1.2Jtd/Zfhx3+ mice
Show the 1 phenotype image(s) involving this allele.
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Germline Transmission: |
Earliest citation of germline transmission:
J:189563
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Parent Cell Line: |
TL1/TL-1 (ES Cell)
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Strain of Origin: |
129S6/SvEvTac
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Allele Type: |
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Targeted (Null/knockout) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: Cre-mediated recombination removed the neo cassette, exon 7 and exon 8. Western blot analysis confirmed the absence of protein expression in mouse embryonic fibroblasts following treatment with a cre-expressing adenovirus.
(J:189563)
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Generation of the Zfhx3tm1.2Jtd allele |
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Zfhx3 Mutation: |
130 strains or lines available
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Original: |
J:189563 Sun X, et al., Heterozygous deletion of Atbf1 by the Cre-loxP system in mice causes preweaning mortality. Genesis. 2012 Nov;50(11):819-27 |
All: |
1 reference(s) |
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