Summary | Mutation origin | Mutation description | Expression | Phenotypes | Tumor data | Find Mice (IMSR) | References

Symbol:	Zfhx3tm1.1Jtd
Name:	zinc finger homeobox 3; targeted mutation 1.1, Jin-Tang Dong
MGI ID:	MGI:5446504
Synonyms:	Atbf1flox
Gene:	Zfhx3  Location: Chr8:109005975-109688268 bp, + strand  Genetic Position: Chr8, 56.02 cM, cytoband E1
Alliance:	Zfhx3tm1.1Jtd page

Germline Transmission:	Earliest citation of germline transmission: J:189563
Parent Cell Line:	TL1/TL-1 (ES Cell)
Strain of Origin:	129S6/SvEvTac

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: A loxP site was inserted upstream of exon 7. A FRT-flanked neo cassette with a 3' loxP site was inserted downstream of exon 8. Flp-mediated recombination removed the neo cassette and left exons 7 and 8 floxed. (J:189563)

Generation of the Zfhx3tm1.1Jtd allele

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

List all tumor models in MMHCdb carrying Zfhx3tm1.1Jtd

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Zfhx3 Mutation:	130 strains or lines available

Original:	J:189563 Sun X, et al., Heterozygous deletion of Atbf1 by the Cre-loxP system in mice causes preweaning mortality. Genesis. 2012 Nov;50(11):819-27
All:	10 reference(s)