Sphk2tm1Cgh
Targeted Allele Detail
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| Symbol: |
Sphk2tm1Cgh |
| Name: |
sphingosine kinase 2; targeted mutation 1, Shaun R Coughlin |
| MGI ID: |
MGI:5445088 |
| Gene: |
Sphk2 Location: Chr7:45358891-45367426 bp, - strand Genetic Position: Chr7, 29.45 cM
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| Alliance: |
Sphk2tm1Cgh page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:120783
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| Parent Cell Line: |
RF8 (ES Cell)
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| Strain of Origin: |
129S4/SvJae
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| Allele Type: |
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Targeted (Conditional ready, No functional change) |
| Mutation: |
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Insertion
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Mutation details: An FRT-flanked neo cassette with a single 3' loxP site was inserted between exons 1 and 2 and an additional loxP site was inserted downstream of exon 5. The neo cassette was subsequently removed through flp mediated recombination.
(J:129783)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Sphk2 Mutation: |
38 strains or lines available
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| Original: |
J:120783 Pappu R, et al., Promotion of lymphocyte egress into blood and lymph by distinct sources of sphingosine-1-phosphate. Science. 2007 Apr 13;316(5822):295-8 |
| All: |
4 reference(s) |
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Analysis Tools
