Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Zfp36tm4.1Pjb
Name:	zinc finger protein 36; targeted mutation 4.1, Paul J Blackshear
MGI ID:	MGI:5441582
Synonyms:	Zfp36flox, Zfp36tm1.1Xen
Gene:	Zfp36  Location: Chr7:28076208-28078680 bp, - strand  Genetic Position: Chr7, 16.72 cM
Alliance:	Zfp36tm4.1Pjb page

Germline Transmission:	Earliest citation of germline transmission: J:188677
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	C57BL/6

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: A floxed neo cassette was inserted upstream of the exon 2. An additional loxP site was inserted downstream of the exon 2. Cre-mediated recombination removed the neo cassette and left exon 2 floxed. (J:188677)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

6 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Zfp36 Mutation:	16 strains or lines available

Original:	J:188677 Qiu LQ, et al., Myeloid-specific tristetraprolin deficiency in mice results in extreme lipopolysaccharide sensitivity in an otherwise minimal phenotype. J Immunol. 2012 May 15;188(10):5150-9
All:	12 reference(s)