Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Il27tm1Lex
Name:	interleukin 27; targeted mutation 1, Lexicon Genetics
MGI ID:	MGI:5440910
Gene:	Il27  Location: Chr7:126188182-126194113 bp, - strand  Genetic Position: Chr7, 69.18 cM
Alliance:	Il27tm1Lex page

Germline Transmission:	Earliest citation of germline transmission: J:187660
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129S/SvEv
Project Collection:	Lexicon

Allele Type:    Targeted (Null/knockout, Reporter) Mutations:    Insertion, Intragenic deletion     A lacZ/neo cassette replaced exons 2 and 3. (J:187660)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Il27 Mutation:	20 strains or lines available

Original:	J:187660 Hall AO, et al., The Cytokines Interleukin 27 and Interferon-gamma Promote Distinct Treg Cell Populations Required to Limit Infection-Induced Pathology. Immunity. 2012 Sep 21;37(3):511-23
All:	3 reference(s)