Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Mfn2tm1.1Arte
Name:	mitofusin 2; targeted mutation 1.1, TaconicArtemis
MGI ID:	MGI:5440839
Synonyms:	Mfn2loxP
Gene:	Mfn2  Location: Chr4:147958056-147989161 bp, - strand  Genetic Position: Chr4, 78.56 cM
Alliance:	Mfn2tm1.1Arte page

Germline Transmission:	Earliest citation of germline transmission: J:188337
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: A loxP site and FRT flanked neo cassette were inserted upstream of exon 5 and a loxP site was inserted downstream of exon 5 via homologous recombination. Flp mediated recombination removed the neo cassette. (J:188337)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mfn2 Mutation:	26 strains or lines available

Original:	J:188337 Lee S, et al., Mitofusin 2 is necessary for striatal axonal projections of midbrain dopamine neurons. Hum Mol Genet. 2012 Nov 15;21(22):4827-35
All:	7 reference(s)