Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Gt(ROSA)26Sortm1(Ctnnb1)Kem
Name:	gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Rolf Kemler
MGI ID:	MGI:5440173
Gene:	Gt(ROSA)26Sor  Location: Chr6:113044389-113054205 bp, - strand  Genetic Position: Chr6, 52.73 cM
Alliance:	Gt(ROSA)26Sortm1(Ctnnb1)Kem page

Germline Transmission:	Earliest citation of germline transmission: J:187739
Parent Cell Line:	W4 (ES Cell)
Strain of Origin:	129S6/SvEvTac

Allele Type:    Targeted (Conditional ready, Inserted expressed sequence) Mutation:    Insertion   Gt(ROSA)26Sortm1(Ctnnb1)Kem expresses 1 gene Knock-in expresses: Organism Expressed Gene Note mouse Ctnnb1 (MGI:88276)   Mutation details: A splice acceptor site, floxed beta-geo stop cassette and a full length Ctnnb1 gene were inserted via homologous recombination. (J:187739)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:	942 strains or lines available

Original:	J:187739 Rudloff S, et al., Differential requirements for beta-catenin during mouse development. Development. 2012 Oct;139(20):3711-21
All:	1 reference(s)