Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Actbtm1Itl
Name:	actin, beta; targeted mutation 1, inGenious Targeting Laboratory
MGI ID:	MGI:5438548
Synonyms:	ActbM
Gene:	Actb  Location: Chr5:142888870-142892509 bp, - strand  Genetic Position: Chr5, 81.8 cM
Alliance:	Actbtm1Itl page

Germline Transmission:	Earliest citation of germline transmission: J:187804
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129S/SvEv

Allele Type:    Targeted Mutation:    Insertion   Mutation details: Twenty-four copies of the MS2 binding site (MBS) for the bacteriophage MS2 capsid protein and a floxed neo cassette were introduced into the 3' UTR. The MBS copies increase the signal-to-noise ratio of the mRNA. (J:187804)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Actb Mutation:	51 strains or lines available

Original:	J:187804 Lionnet T, et al., A transgenic mouse for in vivo detection of endogenous labeled mRNA. Nat Methods. 2011 Feb;8(2):165-70
All:	4 reference(s)