Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Hprt1tm2(CAG-Myof)Isrd
Name:	hypoxanthine phosphoribosyltransferase 1; targeted mutation 2, Isabelle Richard
MGI ID:	MGI:5438010
Synonyms:	TgMyof
Gene:	Hprt1  Location: ChrX:52077014-52110536 bp, + strand  Genetic Position: ChrX, 29.31 cM, cytoband A6
Alliance:	Hprt1tm2(CAG-Myof)Isrd page

Germline Transmission:	Earliest citation of germline transmission: J:187293
Parent Cell Line:	BPES (ES Cell)
Strain of Origin:	(129-Hprt1b-m3 x C57BL/6)F1

Allele Type:    Targeted (Inserted expressed sequence) Mutation:    Insertion   Hprt1tm2(CAG-Myof)Isrd expresses 1 gene Knock-in expresses: Organism Expressed Gene Note mouse Myof (MGI:1919192)   Mutation details: A transgene containing the mouse cDNA under the control of the ubiquitous CAG promoter was inserted into the locus. (J:187293)

Schematic representation of the Hprt1tm2(CAG-Myof)Isrd allele

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hprt1 Mutation:	1273 strains or lines available

Original:	J:187293 Lostal W, et al., Lack of correlation between outcomes of membrane repair assay and correction of dystrophic changes in experimental therapeutic strategy in dysferlinopathy. PLoS One. 2012;7(5):e38036
All:	1 reference(s)