Summary | Mutation origin | Mutation description | Expression | Find Mice (IMSR) | References

Symbol:	Rab7tm1.1Ywd
Name:	RAB7, member RAS oncogene family; targeted mutation 1.1, Yoh Wada
MGI ID:	MGI:5437840
Synonyms:	Rab7flox
Gene:	Rab7  Location: Chr6:87976088-88022252 bp, - strand  Genetic Position: Chr6, 39.13 cM
Alliance:	Rab7tm1.1Ywd page

Germline Transmission:	Earliest citation of germline transmission: J:187732
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: A loxp site was inserted upstream of exon 2. An FRT- and loxP-flanked neo cassette was inserted downstream of exon 3. Flp-mediated recombination removed the neo cassette and left exons 2 and 3 floxed. (J:187732)

In Mice Carrying this Mutation:

13 assay results

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Rab7 Mutation:	119 strains or lines available

Original:	J:187732 Kawamura N, et al., Delivery of endosomes to lysosomes via microautophagy in the visceral endoderm of mouse embryos. Nat Commun. 2012 Sep 18;3:1071
All:	4 reference(s)