Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Gt(ROSA)26Sortm1.1(Ctnna3,EGFP)Jvh
Name:	gene trap ROSA 26, Philippe Soriano; targeted mutation 1.1, Jolanda van Hengel
MGI ID:	MGI:5437345
Synonyms:	Rosa26alphaTctn
Gene:	Gt(ROSA)26Sor  Location: Chr6:113044389-113054205 bp, - strand  Genetic Position: Chr6, 52.73 cM
Alliance:	Gt(ROSA)26Sortm1.1(Ctnna3,EGFP)Jvh page

Germline Transmission:	Earliest citation of germline transmission: J:187209
Parent Cell Line:	G4 (ES Cell)
Strain of Origin:	(129S6/SvEvTac x C57BL/6NCrl)F1

Allele Type:    Targeted (Inserted expressed sequence, Reporter) Mutation:    Insertion   Gt(ROSA)26Sortm1.1(Ctnna3,EGFP)Jvh expresses 2 genes Knock-in expresses: Organism Expressed Gene Note mouse Ctnna3 (MGI:2661445) mouse Ctnna3 (MGI:2661445)   Mutation details: A targeted vector containing a floxed STOP/neo cassette, the mouse Ctnna3 cDNA, and an IRES-EGFP was inserted into the locus. Cre-mediated recombination removed the STOP/neo cassette and allowed for expression of the cDNA and EGFP. (J:187209)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:	942 strains or lines available

Original:	J:187209 Tyberghein K, et al., Tissue-wide overexpression of alpha-T-catenin results in aberrant trophoblast invasion but does not cause embryonic mortality in mice. Placenta. 2012 Jul;33(7):554-60
All:	1 reference(s)