Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Xdhrenf
Name:	xanthine dehydrogenase; Renal Failure
MGI ID:	MGI:5435289
Synonyms:	RENF
Gene:	Xdh  Location: Chr17:74190890-74257191 bp, - strand  Genetic Position: Chr17, 45.25 cM
Alliance:	Xdhrenf page

Strain of Origin:

C57BL/6J

Allele Type:    Chemically induced (ENU) Mutation:    Single point mutation   Mutation details: This mutation was identified in an ENU screen. DNA sequencing revealed a nonsense mutation at codon 26 that co-segregated with affected RENF mice. (J:187066) Inheritance:    Recessive

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

6 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Xdh Mutation:	100 strains or lines available

Original:	J:187066 Piret SE, et al., A mouse model of early-onset renal failure due to a xanthine dehydrogenase nonsense mutation. PLoS One. 2012;7(9):e45217
All:	1 reference(s)