b2b1436Clo Chemically induced Allele Detail MGI Mouse (MGI:5431500)

b2b1436Clo
Chemically induced Allele Detail

Summary

Symbol:	b2b1436Clo
Name:	Mutant line 1436; Bench to Bassinet Program (B2B/CVDC), mutation 1436 Cecilia Lo
MGI ID:	MGI:5431500
Synonyms:	Baby Beluga
Gene:	b2b1436Clo Location: unknown
Alliance:	b2b1436Clo page

Mutant 1436-002-LA displays situs inversus totalis

Show the 11 phenotype image(s) involving this allele.

Mutation
origin

Strain of Origin:	C57BL/6J
Project Collection:	B2B/CvDC

Mutation
description

Allele Type:		Chemically induced (ENU)
Mutation:		Undefined
		This ENU-induced mutation was isolated in a screen at the University of Pittsburgh.

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Disease models

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available Cell Lines: 0 lines available
Carrying any b2b1436Clo Mutation:	1 strain or line available

Notes

Summative Diagnosis:
Cardiac defects: Heterotaxy with complex congenital heart diseases such as transposition of the great arteries (TGA) and atrioventricular septal defect (AVSD)
Fyler Codes
The Fyler code developed by The Boston Children's Heart Foundation in Boston Children's Hospital provides a hierarchical clinical diagnosis of congenital cardiovascular defects and other disorders. These codes are used to delineate pathology in the mutant mouse models that parallel human disease and can be cross referenced to the International Pediatric and Congenital Cardiac Code (IPCCC) (http://www.ipccc.net/).

Fyler Code ID	Code Description
0190	Heterotaxy Syndrome
0700	D-loop transposition of the great arteries
1100	Atrioventricular canal (endocardial cushion defect)
3804	Congenital heart disease

References

Original:	J:175213 Lo C, Information submitted by the NHLBI Cardiovascular Development Consortium (CvDC), Bench to Bassinet Program (B2B/CvDC). MGI Direct Data Submission (B2B/CvDC). 2011-09-12;
All:	2 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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