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Gt(ROSA)26Sortm1(NOTCH1/GFP)Xhsu
Targeted Allele Detail
Summary
Symbol: Gt(ROSA)26Sortm1(NOTCH1/GFP)Xhsu
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Xiao-Hong Sun
MGI ID: MGI:5430379
Synonyms: ROSA26-stop-N1C
Gene: Gt(ROSA)26Sor  Location: Chr6:113044389-113054205 bp, - strand  Genetic Position: Chr6, 52.73 cM
Alliance: Gt(ROSA)26Sortm1(NOTCH1/GFP)Xhsu page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:185287
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Conditional ready, Inserted expressed sequence, Reporter)
Mutation:    Insertion
 
Gt(ROSA)26Sortm1(NOTCH1/GFP)Xhsu expresses 1 gene
 
Mutation detailsA floxed stop cassette, the SalI-SalI fragment containing the human NOTCH1 intracellular domain (N1C) and GFP sequence were inserted into the locus. (J:185287)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:  942 strains or lines available
References
Original:  J:185287 Wang HC, et al., Enhanced Notch activation is advantageous but not essential for T cell lymphomagenesis in Id1 transgenic mice. PLoS One. 2012;7(2):e32944
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory