b2b1470Clo Chemically induced Allele Detail MGI Mouse (MGI:5430054)

b2b1470Clo
Chemically induced Allele Detail

Summary

Symbol:	b2b1470Clo
Name:	Mutant line 1470; Bench to Bassinet Program (B2B/CVDC), mutation 1470 Cecilia Lo
MGI ID:	MGI:5430054
Synonyms:	LAMP
Gene:	b2b1470Clo Location: unknown
Alliance:	b2b1470Clo page

1470-002-NA displays cleft palate and lip

Show the 6 phenotype image(s) involving this allele.

Mutation
origin

Strain of Origin:	C57BL/6J
Project Collection:	B2B/CvDC

Mutation
description

Allele Type:		Chemically induced (ENU)
Mutation:		Undefined
		This ENU-induced mutation was isolated in a screen at the University of Pittsburgh. (J:175213)

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Disease models

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available Cell Lines: 0 lines available
Carrying any b2b1470Clo Mutation:	1 strain or line available

Notes

Summative Diagnosis:
Non-Cardiac Phenotype: Cleft palate and facial cleft, limb defects comprising polydactyly/syndactyly/oligodactyly

Fyler Codes
The Fyler code developed by The Boston Children's Heart Foundation in Boston Children's Hospital provides a hierarchical clinical diagnosis of congenital cardiovascular defects and other disorders. These codes are used to delineate pathology in the mutant mouse models that parallel human disease and can be cross referenced to the International Pediatric and Congenital Cardiac Code (IPCCC) (http://www.ipccc.net/).

Fyler Code ID	Code Description
4103	Polydactyly
4174	Syndactyly
4876	Cleft palate

References

Original:	J:175213 Lo C, Information submitted by the NHLBI Cardiovascular Development Consortium (CvDC), Bench to Bassinet Program (B2B/CvDC). MGI Direct Data Submission (B2B/CvDC). 2011-09-12;
All:	2 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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