Summary | Mutation origin | Mutation description | Expression | Find Mice (IMSR) | References

Symbol:	Bscl2tm1Lchan
Name:	BSCL2 lipid droplet biogenesis associated, seipin; targeted mutation 1, Lawrence Chan
MGI ID:	MGI:5426997
Synonyms:	Bscl2neofl3
Gene:	Bscl2  Location: Chr19:8814831-8826047 bp, + strand  Genetic Position: Chr19, 5.76 cM
Alliance:	Bscl2tm1Lchan page

Germline Transmission:	Earliest citation of germline transmission: J:183701
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Conditional ready) Mutation:    Insertion   Mutation details: An FRT-flanked neo cassette with a 3' loxP site was inserted upstream of exon 3. An additional loxP site was inserted downstream of exon 3. (J:183701)

In Mice Carrying this Mutation:

220 assay results

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Bscl2 Mutation:	33 strains or lines available

Original:	J:183701 Chen W, et al., Berardinelli-seip congenital lipodystrophy 2/seipin is a cell-autonomous regulator of lipolysis essential for adipocyte differentiation. Mol Cell Biol. 2012 Mar;32(6):1099-111
All:	6 reference(s)