Minpp1tm1Prr
Targeted Allele Detail
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| Symbol: |
Minpp1tm1Prr |
| Name: |
multiple inositol polyphosphate histidine phosphatase 1; targeted mutation 1, Paul R Reynolds |
| MGI ID: |
MGI:2385788 |
| Synonyms: |
Minpp1- |
| Gene: |
Minpp1 Location: Chr19:32463169-32492764 bp, + strand Genetic Position: Chr19, 27.25 cM
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| Alliance: |
Minpp1tm1Prr page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:63930
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| Parent Cell Line: |
E14.1 (ES Cell)
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| Strain of Origin: |
129P2/OlaHsd
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| Allele Type: |
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Targeted (Null/knockout) |
| Mutations: |
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Insertion, Intragenic deletion
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Mutation details: A 2 kb region of the gene including exon 1 and part of intron 1 was replaced with a neomycin resistance cassette via homologous recombination, resulting in deletion of the sequences encoding the active site. Northern blot analysis did not detect gene expression in homozygous mutants. Brain extracts from homozygous mutants contained no detectable enzymatic activity.
(J:63930)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Minpp1 Mutation: |
10 strains or lines available
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| Original: |
J:63930 Chi H, et al., Targeted deletion of Minpp1 provides new insight into the activity of multiple inositol polyphosphate phosphatase in vivo. Mol Cell Biol. 2000 Sep;20(17):6496-507 |
| All: |
1 reference(s) |
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Analysis Tools
