Summary | Mutation origin | Mutation description | Expression | Find Mice (IMSR) | References

Symbol:	Nxnl2tm1.1Tlev
Name:	nucleoredoxin-like 2; targeted mutation 1.1, Thierry Leveillard
MGI ID:	MGI:5426259
Gene:	Nxnl2  Location: Chr13:51325058-51329224 bp, + strand  Genetic Position: Chr13, 26.08 cM, cytoband B1
Alliance:	Nxnl2tm1.1Tlev page

Germline Transmission:	Earliest citation of germline transmission: J:183790
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	BALB/c

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: A loxP site was inserted upstream of exon 1. An FRT-flanked neo cassette with a 5' loxP site was inserted downstream of exon 1. Flp-mediated recombination removed the neo cassette and left exon 1 floxed. (J:183790)

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nxnl2 Mutation:	4 strains or lines available

Original:	J:183790 Jaillard C, et al., Nxnl2 splicing results in dual functions in neuronal cell survival and maintenance of cell integrity. Hum Mol Genet. 2012 May 15;21(10):2298-311
All:	1 reference(s)